BARDA and PeraHealth partner to develop machine learning app to aid in assessments and triage of COVID-19 patients in the Emergency Department

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BARDA is collaborating with PeraHealth, Inc., to develop a mobile and desktop application that can assess the risk of severe outcome in COVID-19 patients and separately within the general medical patient population in hospital emergency departments. This partnership will leverage PeraHealth’s expertise in machine learning (ML)-powered software design to build risk triage tools based on the U.S. Food and Drug Administration (FDA)-cleared Rothman Index (RI), an ML-derived algorithm.

Providing a risk assessment of deterioration for patients entering the emergency department can help health care professionals determine the most appropriate level of care for patients to improve outcomes and optimize hospital resources. The RI Risk Triage app is being developed with partner hospitals to optimize workflow, assess user feedback, and explore feasibility of wide deployment during the pandemic. In addition, the app will also be adapted for non-COVID-19 patient assessment to have continued impact as the pandemic wanes.

During emergency responses to major public health threats such as pandemics, risk assessment and patient triage tools are critical to ensuring that patients are provided the best possible life-saving care. Anticipating patient trajectory and the potential for physiological decompensation can also help optimize the allocation of, at times, very limited resources. The goal of this project is to make this RI Risk Triage app widely available to U.S. hospitals via a Health Insurance Portability and Accountability Act of 1996 (HIPAA)-secure cloud-based application, which could greatly improve response to current health threats and preparedness for future challenges.

This award is one component of BARDA’s DRIVe Medical Countermeasures Portfolio; visit BARDA’s DRIVe Portfolio to learn more.

About PeraHealth:

The following information is provided by the company and does not indicate endorsement by the federal government of the company or its products.

PeraHealth is a SaaS company that uses the Rothman Index to transform the clinical and financial efficiency of healthcare. The Rothman Index is the first algorithm that derives a Universal Patient ScoreTM from the vast amount of data in the electronic medical record to create a picture of any patient’s condition over time – any age, any disease, any care setting. It is the only algorithm proven to reduce mortality in practice. Other results include reducing unplanned transfer to the ICU and reducing readmissions. PeraHealth’s customers are leading hospitals and clinicians who need to identify patients at risk of rapid decline, make decisions about transfer and discharge, predict the risk of severe infection, and improve the overall efficiency and quality of care. For more information, visit

Last Updated: May 05, 2021

COVID-19 Medical Countermeasure Portfolio

This award is one component of BARDA's expanding COVID-19 medical countermeasure portfolio; visit BARDA's COVID-19 Portfolio to learn more.